The herpes virus Fc receptor gE-gI mediates antibody bipolar bridging to clear viral antigens from the cell surface.
The Herpes Simplex Virus 1 (HSV-1) glycoprotein gE-gI mizuno prospect gxc105 is a transmembrane Fc receptor found on the surface of infected cells and virions that binds human immunoglobulin G (hIgG).gE-gI can also participate in antibody bipolar bridging (ABB), a process by which the antigen-binding fragments (Fabs) of the IgG bind a viral antigen